Gianfranco BOCCHINFUSOProfessore Associato SSD: CHIM/02 Chimica FisicaStanza: F1 – 6
He claims a solid expertise in the simulation of complex systems. In particular, his main research area is the investigation of functional and structural properties of biomolecules by means of molecular dynamics simulations. Often he integrates these data with spectroscopic experiments.
His work mainly focuses on:
- protein involved in different pathologies, to evaluate the effects of single point amino acid substitutions on the protein structure and activity as also on the interactions with other biomolecules (e.g. DNA sequences, other proteins or regulatory peptides).
- antimicrobial peptides, in homogeneous and heterogeneous solutions, to clarify their mechanism of action and also other peculiar features that make these molecules promising materials.
- modified carbohydrates to be used in the formulation of tablets for drug release; his activity in this field is the evaluation of the structural perturbation induced by the introduction of functional chemical groups.
In the past, he worked also in different research areas. Between the others: i) the modelling of the structural features of the nucleosome; ii) the design of chemoreceptors for pesticides and food toxins; iii) the physicochemical characterization of materials used in artworks; iv) the investigation by means of quantum mechanics techniques of molecules useful for the OLED production.
He coauthored more than 100 peer-reviewed papers on international journals (for details, see http://scholar.google.it/citations?user=pwQ5YR4AAAAJ&hl=it&cstart=0&pagesize=20 ).
He presented the results of his researches in many national and international congresses, also as invited speaker.
- Pubblicazioni (Scopus) | Pubblicazioni (ART)