Technical Staff

Fabio BERTOCCHI

Categoria: D2TAB Tempo Ind. Tempo Pieno TS
Telefono: (+39) 06 7259 4447 Cellulare: 3207983105

Biographical Info

Titoli di studioCorsi di Formazione dal 2017Competenze tecnico - professionaliLaboratoriCampi di ApplicazioneAttività DidatticaAttività RicercaAltri Incarichi
Perito elettronico
NMR Interlaboratory Comparison Nov.2016 – Mag. 2017
Gestione laboratori didattici.
Coordinamento studenti part time.
Preparazione esercitazione laboratorio.
Coordinamento orari lezioni.
Laboratori Didattici Chimici
Didattica e supporto ricerca
Chimica Generale.
Chimica Analitica.
Chimica Organica.
Chimica Fisica.
Farmacia.
Chimica Ambientale.
PUBBLICAZIONI SCIENTIFICHE:

L. Pizzoferrato, P. Manzi, F. Bertocchi, C. Fanelli, G. Rotilio, and M. Paci – “Solid-State 13C CP MAS NMR Spectroscopy of Mushrooms Gives Directly the Ratio between Proteins and Polysaccharides” – Journal of Agricultural and Food Chemistry – 2000 – vol. 48, number 11, pages 5484-5488.

M. Paci, M. Rossi, P. Manzi, F. Bertocchi, L. Pizzoferrato – “Direct Determination of CIS9, TRANS11 Conjugate Linoleic Acid in Milk and Butter from different animal species by NMR Spectroscopy” in “Proceedings of Technological Innovation and Enhancement of Marginal Products” – C. Grenzi Editore – 2006 – pages 143-150.

F. Bertocchi and M. Paci – “Applications of High-Resolution Solid-State NMR Spectroscopy in Food Science” – Journal of Agricultural and Food Chemistry – 2008 – vol. 56, pages 9317-9327.

F. Bertocchi and M. Paci – “High Resolution solid state NMR spectroscopy of foods” – Basic NMR in Foods Characterization – Brosio Editore – 2009 – pages 109-136.

M. Paci, P. Tagliatesta, F. Bertocchi, T. Eliseo, A. Leoni, G. D’Arcangelo, C. Schillaci – “Studio e caratterizzazione dei principali composti provenienti dalla gassificazione del carbone” – Report RdS 240 – 2011 – Enea – 1-38.

R. Nepravishta, F. Bertocchi, F. Polizio, M. Paci, S. Melino – “Recognition of a metal binding site on the C-terminal region of RTN1-C” – the FEBS Journal – vol. 278 – suppl. 1 – 2011 – P03-102 – pag. 122.

S. Cardaci, S. Rizza, G. Filomeni, R. Bernardini, F. Bertocchi, M. Mattei, M. Paci, G. Rotilio, and M. R. Ciriolo – “Glutamine Deprivation Enhances Antitumor Activity of 3-Bromopyruvate through the Stabilization of Monocarboxylate Transporter-1” – Cancer Research – 2012 – vol. 72, number 17, pages 4526-4536.

RINGRAZIAMENTI:

– Journal of Biomolecular NMR – 30: 211–214, 2004.
“Letter to Editor: Solution structure of the HPV-16 E2 DNA binding domain, a transcriptional regulator with a dimeric β-barrel fold”
Alejandro D. Nadra, Tommaso Eliseo, Yu-Keung Mok, Fabio C.L. Almeida, Mark Bycroft, Maurizio Paci, Gonzalo de Prat-Gay & Daniel O. Cicero.

– Biopolymers – Volume 74, Issue 3, pages 189–198, 15 June 2004
“Solution structure of the cyclic peptide contryphan‐Vn, a Ca2+‐dependent K+ channel modulator”
Tommaso Eliseo, Daniel Oscar Cicero,Cristina Romeo, Maria Eugenia Schininà,Gabriella Raybaudi Massilia, Fabio Polticelli, Paolo Ascenzi and Maurizio Paci

– Intern. Journal of Biological Macromolecules – 33 (2003) 193–201
“Structural rearrangements of the two domains of Azotobacter vinelandii rhodanese upon sulfane sulfur release: essential molecular dynamics, 15N NMR relaxation and deuterium exchange on the uniformly labeled protein”
Daniel Oscar Cicero, Sonia Melino, Maria Orsale, Giuseppe Brancato, Andrea Amadei, Fabio Forlani, Silvia Pagani, Maurizio Paci.

– Biochemical and Biophysical Research Comm. – 303 (2003) 238–246
“Contryphan-Vn: a modulator of Ca2+-dependent K+ channels*”
Gabriella Raybaudi Massilia, Tommaso Eliseo, Francoise Grolleau, Bruno Lapied, Julien Barbier, Roland Bournaud, Jordi Molg, Daniel Oscar Cicero, Maurizio Paci, Maria Eugenia Schinin, Paolo Ascenzi and Fabio Polticelli.

– Eur. J. Biochem. 270, 4208–4215 (2003) _ FEBS 2003
“Azotobacter vinelandii rhodanese – Selenium loading and ion interaction studies”
Sonia Melino, Daniel O. Cicero, Maria Orsale, Fabio Forlani, Silvia Pagani and Maurizio Paci

– J. Agric. Food Chem. – 1999, 47, 4060-4063
“Modification of Structure and Digestibility of Chestnut Starch upon
Cooking: A Solid State 13C CP MAS NMR and Enzymatic Degradation Study”
Laura Pizzoferrato, Giuseppe Rotilio and Maurizio Paci

– Journal of Molecular Catalysis A: Chemical 198 (2003) 57–61
“Remarkable selectivity in the cyclopropanation reactions catalysed by an halogenated iron meso-tetraphenylporphyrin”
Pietro Tagliatesta, Alessandra Pastorini

– J. Agric. Food Chem. – 1998, 46, 438-441
“Structural Modification and Bioavailability of Starch Components As Related to the Extent of Maillard Reaction: An Enzymatic Degradation and a Solid-State 13C CPMAS NMR Study”
Laura Pizzoferrato, Maurizio Paci and Giuseppe Rotilio

– Journal of Organometallic Chemistry – 583 (1999) 80–85
“Metallation of alkynes Part 10. Acetoxymercuration of arylferrocenylethynes*,**”
Lorenzo Carollo, Barbara Floris

– Peptides, Vol. 19, No. 10, pp. 1731–1738, 1998
“The Conformation of Peptide Thymosin a1 in Solution and in a Membrane-like Environment by Circular Dichroism and NMR Spectroscopy. A Possible Model for its Interaction with the Lymphocyte Membrane”
ALESSANDRO GROTTESI, MARCO SETTE, ANNA TERESA PALAMARA, GIUSEPPE ROTILIO, ENRICO GARACI AND MAURIZIO PACI

– Journal of Molecular Catalysis A: Chemical 185 (2002) 127–133
“Electronic and steric effects on the stereoselectivity of cyclopropanation reactions catalysed by rhodium meso-tetraphenylporphyrins”
Pietro Tagliatesta, Alessandra Pastorini

– Intern. Journal of Biological Macromolecules – 29, (2001), 99–105
“Unfolding and inactivation of monomeric superoxide dismutase from E. coli by SDS”
Manuela Bozzi , Andrea Battistoni , Marco Sette , Sonia Melino, Giuseppe Rotilio, Maurizio Paci

– FEBS Letters – 548, (2003), 11-16
“Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy”
Maria Orsale, Sonia Melino, Gian Marco Contessa, Vincent Torre, Giuseppina Andreotti, Andrea Motta, Maurizio Paci, Alessandro Desideri,
Daniel O. Cicero

– European Journal of Pharmaceutical Sciences 63,(2014), 199–203
“Determination of the presence of hyaluronic acid in preparations containing amino acids: The molecular weight characterization”
A.Bellomaria, R.Nepravishta, U.Mazzanti, M.Marchetti, P.Piccioli, M.Paci

– Journal of Magnetic Resonance – 180, (2006), 222–228
“HACACO revisited: Residual dipolar coupling measurements and resonance assignments in proteins”
Daniel O. Cicero, Gian Marco Contessa, Maurizio Paci, Renzo Bazzo

– J. Org. Chem. (1999), 64, 5361-5365
“Manganese Tetraphenylporphyrin-Catalyzed Stereoselective Epoxidation of Thymidine Nucleosides”
Pietro Tagliatesta, Roberta Bernini, Claudia Crestini, Donato Monti, Tristano Boschi, Enrico Mincione and Raffaele Saladino

– FEBS Letters – 483, (2000), 21-26
“Investigation of the active site of Escherichia coli Cu,Zn superoxide dismutase reveals the absence of the copper-coordinated water molecule. Is the water molecule really necessary for the enzymatic mechanism?”
Marco Sette, Manuela Bozzi, Andrea Battistoni, Mauro Fasano, Maurizio Paci, Giuseppe Rotilio

– J. of Pharmaceutical and Biomedical Analysis 88 (2014) 441–446
“Saliva metabolomics by NMR for the evaluation of sport performance”
C. Santone, V.Dinallo, M.Paci, S.D’Ottavio, G. Barbato, S.Bernardini

– Biochemistry (1999), 38, 9626-9633
“Zn2+ Ions Selectively Induce Antimicrobial Salivary Peptide Histatin-5 To Fuse Negatively Charged Vesicles. Identification and Characterization of a Zinc-Binding Motif Present in the Functional Domain†”
Sonia Melino, Stefano Rufini, Marco Sette, Roberto Morero, Alessandro Grottesi, Maurizio Paci and Raffaele Petruzzelli

– Eur. J. Biochem. 270, 4755–4761, (2003)
“Interaction of DAPI with individual strands of trinucleotide repeats Effects on replication in vitro of the AATÆATT triplet”
Edoardo Trotta, Nicoletta Del Grosso, Maura Erba, Sonia Melino, Daniel Cicero and Maurizio Paci

– Biochemistry (2003), 42, 13717-13724
“Structural Characterization by NMR of the Natively Unfolded Extracellular Domain of β-Dystroglycan: Toward the Identification of the Binding Epitope for α-Dystroglycan†”
Manuela Bozzi, Marzia Bianchi, Francesca Sciandra, Maurizio Paci,§,| Bruno Giardina, Andrea Brancaccio and Daniel O. Cicero

– Biochemistry (1998), 37, 3020-3027
“Solution Structure of Glutathione Bound to Human Glutathione Transferase P1-1: Comparison of NMR Measurements with the Crystal Structure†”
Maria Nicotra, Maurizio Paci, Marco Sette, Aaron J. Oakley, Michael W. Parker, Mario Lo Bello, Anna Maria Caccuri, Giorgio Federici and Giorgio Ricci

– Inorg. Chem. (1996), 35, 5570-5576
“Electrochemistry and Spectral Characterization of Oxidized and Reduced (TPPBrx)FeCl Where TPPBrx Is the Dianion of â-Brominated-Pyrrole Tetraphenylporphyrin and x Varies from 0 to 8”
Pietro Tagliatesta, Jun Li, Marie Autret, Eric Van Caemelbecke, Anne Villard, Francis D’Souza and Karl M. Kadish

– Nucleic Acids Research, (1998), Vol. 26, No. 20, 4706–4713
“Solution structure of DAPI selectively bound in the minor groove of a DNA T·T mismatch-containing site: NMR and molecular dynamics studies”
Edoardo Trotta and Maurizio Paci

– THE JOURNAL OF BIOLOGICAL CHEMISTRY – Vol. 271, No. 44, Issue of November 1, pp. 27608–27614, (1996)
“Simultaneous and Different Binding Mechanisms of 4’,6-Diamidino-2-phenylindole to DNA Hexamer (d(CGATCG))2; A 1H NMR STUDY*”
Edoardo Trotta, Ettore D’Ambrosio, Giampietro Ravagnan and Maurizio Paci

– Protein Science, vol. 13, 2437-2445, (2004)
“The effect of an ionic detergent on the natively unfolded β-dystroglycan ectodomain and on its interaction with α-dystroglycan”
MANUELA BOZZI, ENRICO DI STASIO, DANIEL O. CICERO, BRUNO GIARDINA, MAURIZIO PACI AND ANDREA BRANCACCIO

– Food Chemistry – 194, (2016), 733–739
“Profiling proteins in nutraceutical formulations: Characterization of the constituents”
Alessia Bellomaria, Ridvan Nepravishta, Mario Marchetti, Maurizio Paci

– Journal of Biomolecular NMR – (2005) 31: 185–199, Springer 2005 DOI 10.1007/s10858-005-0165-1
“Structure of calmodulin complexed with an olfactory CNG channel fragment and role of the central linker: Residual dipolar couplings to evaluate calmodulin binding modes outside the kinase family”
Gian Marco Contessaa, Maria Orsale, Sonia Melino, Vincent Torre, Maurizio Paci, Alessandro Desideri & Daniel O. Cicero

– Biochemistry (2000), 39, 6799-6808
“The ATT Strand of AATâATT Trinucleotide Repeats Adopts Stable Hairpin Structures Induced by Minor Groove Binding Ligands”
Edoardo Trotta, Nicoletta Del Grosso, Maura Erba and Maurizio Paci

– Organometallics – (1997), 16, 384-391
“Isomer Distribution and Interconversion in Cationic Allylpalladium(II) Complexes with 2-(Iminomethyl)pyridine Ligands”
Bruno Crociani, Simonetta Antonaroli, Maurizio Paci, Francesca Di Bianca, Luciano Canovese

– Biochemistry (2009), 48, 242–253
“Nucleic Acid Binding of the RTN1-C C-Terminal Region: Toward the Functional Role of a Reticulon Protein†”
Sonia Melino, Ridvan Nepravishta, Alessia Bellomaria, Stefania Di Marco and Maurizio Paci

– Cell Death and Differentiation – (1999) 6, 916 – 930
“Transglutaminase crosslinking and structural studies of the human small proline rich 3 protein”
Peter M Steinert, Eleonora Candi, Edit Tarcsa, Lyuben N Marekov, Marco Sette, Maurizio Paci, Barbara Ciani, Pietro Guerrieri and Gerry Melino

– THE J.of BIOLOGICAL CHEMISTRY – Vol.268, No.6, Issue of Feb. 25, pp. 3944-3951, (1993)
“‘H NMR Study of [d(GCGATCGC)]2 and Its Interaction with Minor Groove Binding 4’,6-Diamidino-2-phenylindol”
Edoardo Trotta, Ettore D’Ambrosio, Nicoletta Del Grosso, Giampietro Ravagnan, Maurizio Cirilli and Maurizio Paci

– Main Group Metal Chemistry, (1997), vol.20, No.5, 301-312
“Metallation of Alkynes. Part 8. Substituent Effects in Acetoxymercuration of Diarylethynes”
E Ballico, G Cerichelli, S Fossa, B Floris and F Giordano

– European Mass Spectrometry – 3, 335-360, (1997)
“Fast atom bombardment mass spectral observations on some –halogenated tetraphenylporphyrins and their iron derivates”
T. Boschi, G. D’Arcangelo and P. Tagliatesta

– Nucleic Acid Research – Vol.23, No.8, pp. 1333-1340, (1995)
“Evidence for Dapi intercalation in CG sites of DNA oligomer [d(GCGATCGC)]2 :a‘H NMR Study”
Edoardo Trotta, Ettore D’Ambrosio, Giampietro Ravagnan and Maurizio Paci

– Eur. J. Biochem. – 227, pp. 441-447, (1995)
“A two-dimensional NMR study of bovine Cu, Co superoxide dismutase Further assignments in the region surrounding the active site”
Marco Sette, Maurizio Paci, Alessandro Desideri and Giuseppe Rotilio

– Gazzetta Chimica It. – 122, pp. 1-5, (1992)
“Structure determinationof a double stranded octanucleotide DNA segment by 2D NMR”
Edoardo Trotta, Ettore D’Ambrosio, Nicoletta Del Grosso and Giampietro Ravagnan and Maurizio Paci

– Carbohydrate polymers – (1994)
“NMR Study of paper”
Maurizio Paci, Carlo Federici, Donatella Capitani, Nicoletta Parenze & Anna Laura Segre

– J. Chem.Soc.,Dalton trans. – (1996), 2793-2797
“Synthesis and Electrochemistry of 2,3,7,8,12,13,17,18-octachloro-5,10,15,20-tetrakis(3,5-dichloro-2,6-dimethoxyphenyl)porphiryn (H2tdcdmpp),[Co11(tdcdmpp)] and [M(tdcdmpp)Cl] (M=FeIII or MnIII)”
Marie Autret, Zhongping Ou, Alessandra Antonini Tristano Boschi, Pietro Tagliatesta and Karl M. Kadish

– J. of Polymer S., Part A – vol. 34, (1996), 3417-3425
“New Chemical Hydrogels Based on Poly(vinyl alcohol)*”
Gaio Paradossi, Roberta Lisi, Maurizio Paci and Vittorio Crescenzi

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