Antibody-powered nucleic acid release using a DNA-based nanomachine
Published on Nature Communication a joint study of the Department of Chemical Science and Technologies and the Department of Chemistry of the University of Montreal that demonstrates that by using three different antigens (including one relevant to HIV), it is possible to design different DNA nanomachines regulated by their targeting antibody in a rapid, versatile and highly specific manner. The antibody-powered DNA nanomachines we have developed here may thus be useful in applications like controlled drug-release, point-of-care diagnostics and in vivo imaging.